Significance Of Serum Lactate/Albumin Ratio As An Indicator Of Morbidity And Mortality In Sepsis.

Abstract

INTRODUCTION: Sepsis is a clinical syndrome that occurs as a complication of a severe infection,which is associated with high morbidity and mortality. APACHE II scoring system were used widely to assess outcome in severe sepsis and septic shock but this is time consuming, expensive and lengthy process having multiple variables to calculate, so it is very impractical to use APACHE II scoring system in busy emergency room. The association of APACHE II score, serum lactate albumin ratio value will be examined in our study. This study aimed at investigating the lactate/albumin ratio as a prognostic marker of Sepsis MATERIAL AND METHODS: A total of 120 patients with sepsis were inpatients of R.L Jalappa hospital were included in the study. Each patient who is admitted in intensive care unit (ICU), medical intensive care unit (MICU) Acute physiological and chronic health evaluation (APACHE) II score was calculated. Serum Lactate, serum albumin and serum lactate albumin ratio was calculated within rst 6 hours period. The association of APACHE II score, serum lactate value, serum albumin value and serum lactate albumin ratio value was examined. RESULTS: The mean Lactate/Albumin ratio was found to be increased in patients with sepsis/septicemic shock. On correlating between APACHE II score and serum lactate Albumin ratio p value was signicant.CONCLUSION: This study indicates that serum lactate albumin ratio shows strong correlation with APACHEII score in predicting mortality in severe sepsis and septic shock.