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DC Field | Value | Language |
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dc.contributor.author | H.S Brindha, Azeem SM, T.N.Suresh. | - |
dc.date.accessioned | 2023-12-18T05:54:52Z | - |
dc.date.available | 2023-12-18T05:54:52Z | - |
dc.date.issued | 2020-08 | - |
dc.identifier.uri | http://172.16.4.202:8080/xmlui/handle/123456789/8431 | - |
dc.description.abstract | Abstract (1) To determine tumor volume by clinical measurement, imaging and histopathological examination in patients with squamous carcinoma of buccal mucosa. (2) To correlate tumor volume with lymph-node metastasis and loco-regional control. Retrospective Observational Study. Rural tertiary care hospital. 75 Patients undergoing surgery for T2 (68%) and T3 (32%) Oral squamous carcinomas were included in this observational study. Tumor volume—a product of maximum length, breadth and thickness, was determined clinically and by imaging. Tumor volume on histopathology was documented and correlated with lymph-node metastasis. After 13 months minimum follow-up, tumor volume was correlated with loco-regional control. Recurrences were analysed with regard to tumor volume, depth of invasion, lymph-node metastasis and resection margins. Average tumor volume was 7.1 cm3among T2 and 14.4 cm3among T3. 25% of T2 tumors had metastatic lymph-nodes compared to 33.3% in T3. There was positive correlation between tumor volume and lymph-node metastasis. Lymph-node metastasis was absent when tumor volume was\8 cm3. There were 4 local and 2 regional recurrences in this study. Average histopathological tumor volume among patients who had local recurrence was 12.95 cm3. Regional recurrences occurred in tumors staged N2b and N3b on histopathology. Average depth of invasion in patients with recurrence was 10.33 mm.. Tumor volume represents actual tumor load and correlates with lymph node metastasis and prognosis in oral cancers. Depth of invasion and tumor thickness influence staging and prognosis. Large volume tumors have poor oncological outcome. | en_US |
dc.language.iso | en | en_US |
dc.subject | Tumour volume Buccal mucosa Squamous cell carcinoma Tumour thickness Depth of invasion Lymph node metastasis | en_US |
dc.title | Evaluation of Tumour Volume as a Prognostic Factor in Carcinoma Buccal Mucosa | en_US |
dc.type | Article | en_US |
Appears in Collections: | ENT |
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File | Description | Size | Format | |
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Evaluation of Tumour Volume as a Prognostic Factor in Carcinoma Buccal Mucosa..pdf | 472.56 kB | Adobe PDF | View/Open |
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