CORRELATIVE STUDY OF CORONARY ARTERY DISEASE SEVERITY AND GLYCOSYLATED HEMOGLOBIN IN DIABETIC AND NON-DIABETIC PATIENTS

Abstract

BACKGROUND: Diabetes mellitus and coronary heart disease are closely associated with each other and generally coexist. The severity of coronary artery disease is related directly to the quality of glucose control in diabetic patients. AIMS: To correlate coronary artery disease severity and glycosylated hemoglobin in diabetic and non-diabetic patients. MATERIALS & METHODS: Descriptive observational cross-sectional study conducted for a period of 1.5 years from January 2019 to June 2020. A total of 400 subjects were included in the final analysis. RESULTS: The mean age of the participants was 57.97 ± 11.59. The majority of the participants were males with 82.25%. ST-elevation MI, non-ST elevation MI, unstable angina, and stable angina were the clinical presentation identified with 61.25%, 18.5%, 11.25%, and 9% respectively. Troponin I was elevated in 80.5% of the participants. NSTEMI and STEMI were identified in 18.5% and 61.25% of the participants. The mean of LV Function in the study population was 47.32 ± 10.15. Among the study population, LMCA was identified in 9.25% whereas, Whereas, LCX, and RCA in 52.25% and 65%. The mean of Hba1C in the study population was 7.47 ± 2.26. CONCLUSION: Increased HbA1c levels in the diabetes group was significantly associated with the severity of CAD.