A Gender Based Case Control Study of Anthropometric and Renal Profile in Rural Diabetic Population

Abstract

OBJECTIVE: To evaluate the gender specific changes in anthropometric and renal parameters for the prediction of microvascular complications commonly diabetic nephropathy at its earlier stages through screening of diabetic patients. MATERIALS AND METHODS: We studied total 150 subjects with Type 2 diabetes mellitus, duration of diabetes within 10 years, age group 50-60 years and equal number of age and gender matched clinically proven healthy controls during March 2011 to January 2012 were enrolled in our study. Anthropometric and biochemical parameters measurements were done by standard methods. RESULTS: On comparison between non diabetics and diabetic subjects, waist circumference (WC), body mass index (BMI), waist hip ratio (WHR), obesity index, diastolic blood pressure (DBP), fasting blood sugar (FBS), serum creatinine, spot urine albumin (AER)and albumin/creatinine ratio (ACR) were significantly higher in diabetic males compared to non diabetic males and WC, BMI, DBP, FBS and SCr were significantly higher in diabetic females on comparison with non diabetic females. In Normoalbuminuric group (ACR<30mg/g) WHR and AER was higher in males compared to females and in Microalbuminuric group (ACR 30- 300mg/g)WHR, AER, FBS and ACR were significantly higher in males compared to females. CONCLUSION: Significant increase in WHR was observed between male and female diabetics above the cutoff values as per the recommendations made by National Institute of Health Guidelines, and this study also confirmed that AER was higher in diabetic males compared to females which are clinical hallmarks for diabetic nephropathy and cardiovascular risk factors.